IFNA2 Monoclonal Antibody (OTI12C7), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-4325	100 μL

Catalog No. 50-168-4325 Supplier OriGene Supplier No. TA811910

Description

Mouse Monoclonal Antibody

IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor component result in the activation of a number of signaling pathways which are mainly involved in innate immune response against viral infection. In humans, the gene for IFN alpha is located on on chromosome 9. The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. IFN alpha is produced primarily by plasmacytoid dendritic cells, is a potent component of the anti-viral innate immune response and modulates adaptive immunity. Diseases associated with the dysfunction of IFN alpha include Hepatitis C and Hepatitis.

Specifications

• Antigen: IFNA2
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI12C7
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: IFNA2
• Gene Accession No.: P01563
• Gene Alias: IFN-alphaA, IFNA, IFNA2B, INFA2
• Gene Symbols: IFNA2
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 24-188 of human IFNA2 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3440
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1