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  6. IgE Mouse anti-Human, Brilliant Violet 421, Clone: G7-26, BD

IgE Mouse anti-Human, Brilliant Violet 421, Clone: G7-26, BD

Catalog No. bdb566324 Shop All BD Biosciences Products
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Description

Mouse Monoclonal Antibody

The G7-26 monoclonal antibody specifically recognizes the constant region of human Immunoglobulin E (IgE). It does not crossreact with other immunoglobulin heavy chain isotypes. IgE exists in a transmembrane form that is expressed by B lymphocytes and serves as an antigen receptor. Soluble IgE is produced and secreted by activated B cells and plasma cells. IgE may bind through its constant region to cell surface receptors, such as the high-affinity ( ) or low-affinity ( /CD23) receptors for IgE. Fc RI is expressed on mast cells, basophils, and at lower levels, on dendritic cells and monocytes.

The antibody was conjugated to BD Horizon BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407nm and Em Max at 421nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates. BV421 is a polymer-based dye excited by the violet laser and is one of the brightest fluorochromes offered by BD Biosciences. Conjugates are typically 10 times brighter than Pacific Blue™ conjugates and are often as bright as or brighter than PE conjugates. Due to nearly identical excitation and emission properties but different spillover characteristics, BD Horizon BV421, Pacific Blue™, and BD Horizon™ V450 cannot be used simultaneously.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IgE
Classification Monoclonal
Clone G7-26
Conjugate Brilliant Violet 421
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Gene Alias Immunoglobulin E, IGHE, IGHε, Ig epsilon chain constant region
Host Species Mouse
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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