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IGF1B Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501732772 Shop All Proteintech Group Inc Products
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50-173-2772 150 μL
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Catalog No. 50-173-2772 Supplier Proteintech Group Inc Supplier No. 202151AP150UL
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Description

Rabbit Polyclonal Antibody

The antibody is specific to isoform IGF-1B.

Insulin-like growth factor-1 (IGF1), is structurally and functionally related to insulin but has a much higher growth-promoting activity. A variety of cellular responses are induced by IGF1, including cell proliferation, differentiation, migration, and survival. IGF1 stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regards to enhancing glucose uptake. In circulation, IGFs are predomitly bound to binding proteins (IGFBPs) which prolong the half-life of the IGFs and play a role in delivering them to target tissues. Low levels of IGF1 have been linked to Alzheimer′s disease.

Specifications

Antigen IGF1B
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.44 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene IGF1
Gene Accession No. P05019
Gene Alias IBP1, IGF I, IGF1, IGF1A, IGF1B, IGFI, Insulin like growth factor I, Mechano growth factor, MGF, Somatomedin C
Gene Symbols IGF1
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3479
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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