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  6. IGF1R beta chain Mouse anti-Human, Rat, Clone: 3C6A11, Proteintech 

IGF1R beta chain Mouse anti-Human, Rat, Clone: 3C6A11, Proteintech
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Catalog No. 501736715 Shop All Proteintech Group Inc Products
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50-173-6715 150 μL
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Catalog No. 50-173-6715 Supplier Proteintech Group Inc Supplier No. 662831IG150UL
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Description

Mouse Monoclonal Antibody

This antibody raised against a synthesized polypeptide (CGVLVLRASFDERQPYAH) corresponding to 1332-1348aa of human IGF1R protein recognizes beta chain of IGF1R.

IGF1R (Insulin-like Growth Factor1 Receptor) is a receptor tyrosine kinase that mediates actions of insulin-like growth factor 1 (IFG1). It binds IGF1 with high affinity and IGF2/insulin with lower affinity. Activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survial of maligt cells. Ligand binding activates the receptor kinase and leads to receptor autophosphorylation and tyrosines phosphorylation of multiple substrates that function as signaling adapter proteins.

Specifications

Antigen IGF1R beta chain
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 3C6A11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene IGF1R
Gene Accession No. P08069, P24062
Gene Alias CD221, IGF I receptor, IGF1R, IGF1R-Specific, IGFIR, IGFR, JTK13
Gene Symbols IGF1R
Host Species Mouse
Immunogen Peptide
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25718, 3480
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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