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Invitrogen™ IGF2BP2 Polyclonal Antibody
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Catalog No. PIPA529869
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100 μL
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PIPA529869 100 μL
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Catalog No. PIPA529869 Supplier Invitrogen™ Supplier No. PA529869
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, HepG2. Predicted reactivity: Mouse (92%), Rat (92%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family. It recruits target transcripts to cytoplasmic protein-RNA complexes. The protein contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IGF2BP2
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene IGF2BP2
Gene Accession No. Q5SF07, Q9Y6M1
Gene Alias C330012H03Rik; Hepatocellular carcinoma autoantigen p62; IGF2 mRNA-binding protein 2; IGF2BP2; IGF-II mRNA-binding protein 2; Imp2; IMP-2; insulin like growth factor 2 mRNA binding protein 2; insulin-like growth factor 2 mRNA binding protein 2; insulin-like growth factor 2 mRNA-binding protein 2; insulin-like growth factor 2, binding protein 2; Neilsen; p62; RGD1305614; VICKZ family member 2; VICKZ2
Gene Symbols IGF2BP2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human IGF2BP2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10644, 319765
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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