Invitrogen™ IGFBP2 Recombinant Rabbit Monoclonal Antibody (106)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA531156

Catalog No. PIMA531156

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Mouse IGFBP-2/IGFBP2.

IGFBP2 (insulin-like growth factor binding protein 2) is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.

Specifications

• Antigen: IGFBP2
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P47877
• Gene Symbols: IGFBP2
• Immunogen: Recombinant Mouse IGFBP-2/IGFBP2 Protein (Met1-Gln305).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA
• Clone: 106
• Conjugate: Unconjugated
• Gene: IGFBP2
• Gene Alias: AI255832; BP2; BRL-BP; IBP2; IBP-2; IGF binding protein 2; IGF-binding protein 2; IGFBP; IGFBP2; IGFBP-2; IGF-BP53; ILGFBPA; Insulin like growth factor binding protein; insulin like growth factor binding protein 2; insulin-like growth factor binding protein 2; insulin-like growth factor binding protein 2, 36kDa; insulin-like growth factor-binding protein 2; mIGFBP-2; OTTHUMP00000207753
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 16008
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid