Invitrogen™ IGSF3 Monoclonal Antibody (503621)

Catalog No.	Quantity
PIMA524216	100 μg

Catalog No. PIMA524216 Supplier Invitrogen™ Supplier No. MA524216

Description

Mouse Monoclonal Antibody

In direct ELISAs, no cross-reactivity with recombinant human (rh) IGSF4, 4B, 4C, 4D or 8 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

IGSF3 (immunoglobulin superfamily, member 3), also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function.

Specifications

• Antigen: IGSF3
• Applications: Flow Cytometry, Western Blot
• Classification: Monoclonal
• Clone: 503621
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5% trehalose and No Preservative
• Gene: IGSF3
• Gene Accession No.: O75054
• Gene Alias: 1700016K10Rik; 2810035F16Rik; 4833439O17Rik; EWI3; EWI-3; Glu-Trp-Ile EWI motif-containing protein 3; Igsf3; immunoglobin superfamily, member 3; immunoglobulin superfamily member 3; immunoglobulin superfamily, member 3; Kiaa0466; LCDD; mKIAA0466; RP4-781D12.1; V8
• Gene Symbols: IGSF3
• Host Species: Mouse
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human IGSF3 Gln20-Ala1125.
• Purification Method: Protein A/G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3321
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1