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Invitrogen™ IGSF3 Monoclonal Antibody (503621)
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Catalog No. PIMA524216
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100 μg
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Catalog No. Quantity
PIMA524216 100 μg
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Catalog No. PIMA524216 Supplier Invitrogen™ Supplier No. MA524216
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Description

Mouse Monoclonal Antibody

In direct ELISAs, no cross-reactivity with recombinant human (rh) IGSF4, 4B, 4C, 4D or 8 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

IGSF3 (immunoglobulin superfamily, member 3), also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IGSF3
Applications Flow Cytometry, Western Blot
Classification Monoclonal
Clone 503621
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene IGSF3
Gene Accession No. O75054
Gene Alias 1700016K10Rik; 2810035F16Rik; 4833439O17Rik; EWI3; EWI-3; Glu-Trp-Ile EWI motif-containing protein 3; Igsf3; immunoglobin superfamily, member 3; immunoglobulin superfamily member 3; immunoglobulin superfamily, member 3; Kiaa0466; LCDD; mKIAA0466; RP4-781D12.1; V8
Gene Symbols IGSF3
Host Species Mouse
Immunogen Mouse myeloma cell line NS0-derived recombinant human IGSF3 Gln20-Ala1125.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3321
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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