IKZF3 Monoclonal Antibody (OTI5E2), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-0227	100 μL

Catalog No. 50-168-0227 Supplier OriGene Supplier No. TA804394

Description

Mouse Monoclonal Antibody

IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.

Specifications

• Antigen: IKZF3
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI5E2
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: IKZF3
• Gene Accession No.: Q9UKT9
• Gene Alias: AIO, AIOLOS, ZNFN1A3
• Gene Symbols: IKZF3
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-301 of human IKZF3 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 22806
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1