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IKZF3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501732327 Shop All Proteintech Group Inc Products
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50-173-2327 150 μL
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Catalog No. 50-173-2327 Supplier Proteintech Group Inc Supplier No. 190551AP150UL
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Rabbit Polyclonal Antibody

IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.

Specifications

Antigen IKZF3
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.16 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene IKZF3
Gene Accession No. O08900, Q9UKT9
Gene Alias AIO, AIOLOS, IKZF3, Zinc finger protein Aiolos, ZNFN1A3
Gene Symbols Ikzf3
Host Species Rabbit
Immunogen IKZF3 Fusion Protein Ag5537
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22780, 22806, 303511
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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