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Genscript Corporation Antibody Protein Proteins Proteins 5 UG 1/EA

Supplier:  Genscript Corporation Z031085

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Interleukin-11 is a pleiotropic cytokine that was originally detected in the conditioned medium of an IL-1Alpha-stimulated primate bone marrow stromal cell line (PU-34) as a mitogen for the IL-6-responsive mouse plasmacytoma cell line T11. IL-11 has multiple effects on both hematopoietic and non-hematopoietic cells. Many of the biological effects described for IL-11 overlap with those for IL-6. In vitro IL-11 can synergize with IL-3 IL-4 and SCF to shorten the G0 period of early hematopoietic progenitors. IL-11 also enhances the IL-3-dependent megakaryocyte colony formation. IL-11 has been found to stimulate the T cell-dependent development of specific immunoglobulin-secreting B cells.

Catalog No. 50-252-9832


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