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BioVendor, LLC Interleukin-12 (IL-12p70), High Sensitivity Human ELISA (96 wells)
Supplier: BioVendor, LLC RGP016R
Interleukin-12 (IL-12p70) Human ELISA, High Sensitivity, 96 wells. Research use only. Sensitive immunoassay kit for in vitro quantitative measurement natural or recombinant human IL-12 p70 heterodimer in serum, plasma, buffered solutions or cell culture media. Calibration range: 0.7825 pg/ml. Detection limit < 0.75 pg/ml. Synonyms: IL12, IL-12p70, cytotoxic lymphocyte maturation factor, CLMF, natural killer cell stimulatory factor, NKSF. Summary: IL-12 is a pleiotropic cytokine composed of p35 and p40 subunits, which, when combined together form the bioactive IL-12p70. IL-12 is a potent regulator of cell-mediated immune responses and it induces IFN-gamma production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue-type mast cells. Among its biological activities, IL-12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells, and induces the development of IFN-gamma-producing Th1 cells.
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