Invitrogen™ IL-13 Monoclonal Antibody (JES10-5A2)

Catalog No.	Quantity
AHC0132	500 μg

Catalog No. AHC0132 Supplier Invitrogen™ Supplier No. AHC0132

Description

Rat Monoclonal Antibody

IL-13 Monoclonal Antibody for Western Blot, IHC, Flow, ELISA, Neu

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.

Specifications

• Antigen: IL-13
• Applications: ELISA, Flow Cytometry, Immunohistochemistry, Neutralization, Western Blot
• Classification: Monoclonal
• Clone: JES10-5A2
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene: Il13
• Gene Accession No.: P35225
• Gene Alias: ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600
• Gene Symbols: Il13
• Host Species: Rat
• Immunogen: Purified recombinant human IL-13.
• Purification Method: Purified
• Quantity: 500 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3596
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1

Frequently Asked Questions (FAQs)

Which antibodies directed to cytokines are suitable for use in immunohistochemistry with paraffin sections?

The following antibodies have been used successfully for IHC with paraffin sections:
Mouse (monoclonal) Anti-Human TGF-?1 (Cat. No. AHG0051), Rat (monoclonal) Anti-Human Interleukin-13 (Cat. No. AHC0132), Rabbit (polyclonal) Anti-Human IL-8 (Cat. No. AHC0881), Rabbit (polyclonal) Anti-Mouse Interferon-? (Cat. No. AMC4034), Goat (polyclonal) Anti-Mouse TNF-? (Cat. No. AMC3012), and Rabbit (polyclonal) Anti-Rat TNF-? (Cat. No. ARC3012).

You can also locate these and other antibodies with our helpful Primary Antibody Selection Guide. This can be accessed by searching "Primary Antibody Selector Tool" on our website. Once you've reached the Selection Guide, you can narrow the search by clicking on your desired links at the top of the Guide.

Do you have a neutralizing monoclonal antibody for human IL-13?

Yes, the IL-13 Monoclonal Antibody (JES10-5A2) (Cat. No. AHC0132), clone ID JES10-5A2, has a neutralizing activity against human IL-13.

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov