IL-17E Monoclonal Antibody (11K8B1), Rockland™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-199-1354	Rockland Immunochemicals 209301C58	100 μg
50-199-1355	Rockland Immunochemicals 209301C58S	25 μL

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This antibody is specific for human IL-17E protein. A BLAST analysis was used to suggest cross-reactivity with IL-17E from human sources based on 100% homology with the immunizing sequence. Cross-reactivity with IL-17E from other sources has not been determined.

Interleukin 25 (IL-25) is a member of the IL-17 family and is identified as a proinflammatory cytokine which is produced by Th17 effector cells thus enabling the Th17 subset to initiate or maintain the autoimmune process in diseases such as Rheumatoid Arthritis. IL-25 also induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. IL-25 itself is activated through IL-23, IL-5, and TGF-beta.

Specifications

• Antigen: IL-17E
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene Alias: IL17E; IL-17E; IL25; IL-25; ILN; Interleukin; interleukin 17E; interleukin 25; Interleukin-17E; Interleukin-25; RGD1561632; UNQ3120/PRO10272
• Gene Symbols: IL25
• Isotype: IgG1
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Gene: IL25

• Clone: 11K8B1
• Applications: ELISA, Flow Cytometry, Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: Q9H293
• Gene ID (Entrez): 64806
• Immunogen: Anti-IL-17E (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17E produced in E.coli followed by hybridoma development.
• Primary or Secondary: Primary
• Product Type: Antibody