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  6. Invitrogen™ IL-19 Monoclonal Antibody (RN19), eBioscience™, Invitrogen™ 

Invitrogen™ IL-19 Monoclonal Antibody (RN19), eBioscience™, Invitrogen™
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Catalog No. 5013660
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50 μg
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Catalog No. Quantity
50-136-60 50 μg
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Catalog No. 50-136-60 Supplier Invitrogen™ Supplier No. 14719181
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Description

Rat Monoclonal Antibody

Description: The RN19 antibody reacts with mouse interleukin-19 (IL-19), a member of the IL-10 family, which is secreted by activated keratinocytes and monocytes. Applications Reported: The RN19 antibody has been reported for use in ELISA capture of mouse IL-19. Applications Tested: The RN19 antibody has been tested as the capture antibody in a sandwich ELISA for analysis of mouse Interleukin-19 (IL-19) in combination with a biotinylated polyclonal anti-mouse IL-19 antibody for detection. A suitable range of concentrations of this antibody for ELISA capture is 1.0-4 μg/mL. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 4000 pg/mL - 30 pg/mL should be included in each ELISA plate. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.

The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.
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Specifications

Antigen IL-19
Applications ELISA
Classification Monoclonal
Clone RN19
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene IL19
Gene Accession No. Q8CJ70
Gene Alias il 19; IL-10C; IL19; IL-19; ILN; Interleukin; interleukin 19; Interleukin19; interleukin-19; MDA1; MDA-1; melanoma differentiation associated protein-like protein; melanoma differentiation-associated protein-like protein; NG.1; ZMDA1
Gene Symbols IL19
Host Species Rat
Purification Method Affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 329244
Target Species Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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For Research Use Only.

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