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Invitrogen™ IL-2 Monoclonal Antibody (MQ1-17H12), APC, eBioscience™
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Catalog No. 5015298
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25 Tests
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Catalog No. Quantity
50-152-98 25 Tests
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Catalog No. 50-152-98 Supplier Invitrogen™ Supplier No. 17702941
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Description

Rat Monoclonal Antibody

Description: The MQ1-17H12 antibody reacts with human interleukin-2 (IL-2), a 17 kDa T cell growth factor and a major immunoregulatory cytokine. The MQ1-17H12 antibody is a non-neutralizing antibody. Applications Reported: MQ1-17H12 has been reported for use in staining of intracellular IL-2. Applications Tested: This MQ1-17H12 antibody is tested by intracellular staining and flow cytometric analysis of activated human normal human peripheral blood cells.This product has been pre-titrated and tested intracellular staining and flow cytometric analysis of activated human normal human peripheral blood cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
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Specifications

Antigen IL-2
Applications Flow Cytometry
Classification Monoclonal
Clone MQ1-17H12
Concentration 5 μL/Test
Conjugate APC
Formulation PBS with BSA and 0.09% sodium azide; pH 7.2
Gene IL2
Gene Accession No. P60568
Gene Alias aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
Gene Symbols IL2
Host Species Rat
Purification Method Affinity chromatography
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3558
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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