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  6. IL-2 Rat anti-Mouse, APC, Clone: JES6-5H4, BD

IL-2 Rat anti-Mouse, APC, Clone: JES6-5H4, BD

Catalog No. p-7092756 Shop All BD Biosciences Products
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25 μg
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BDB562041 25 μg
BDB554429 0.1 mg
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Catalog No. BDB562041 Supplier BD Biosciences Supplier No. 562041
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Description

Rat Monoclonal Antibody

The JES6-5H4 monoclonal antibody specifically binds to mouse interleukin-2 (IL-2). IL-2 is a multifunctional cytokine that plays pivotal roles in immunity and tolerance. It is produced by activated T cells. IL-2 effects the activation, growth, proliferation and/or differentiation of various cell types including T and B lymphocytes and their precursors, LAK cells, NK cells, and monocytes/macrophages. IL-2 mediates its biological activities by binding to IL-2 receptor compleses. The intermediate affinity IL-2R is comprised of IL-2R β (CD122) and common gamma chain ( γc; CD132) subunits whereas the high-affinity IL-2R is comprised of IL-2R α (CD25), IL-2R β and γc subunits. The JES6-5H4 monoclonal antibody binds to IL-2 and neutralizes its biological activity.

TRUSTED_SUSTAINABILITY

Specifications

Antigen IL-2
Applications Flow Cytometry
Classification Monoclonal
Clone JES6-5H4
Concentration 0.2mg/mL
Conjugate APC
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse IL-2 Recombinant Protein
Purification Method Affinity Purified
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2b
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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