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IL-5 Monoclonal Antibody (TRFK4), Biotin, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

$164.00 - $419.00

Specifications

Antigen IL-5
Clone TRFK4
Concentration 0.5 mg/mL
Applications Immunostaining
Classification Monoclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-121-59
Encompass_Preferred
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Invitrogen™
13705181
50 μg
Each for $164.00
Only null left
Add to Cart
 
50-121-60
Encompass_Preferred
View Documents
Invitrogen™
13705185
500 μg
Each for $419.00
Only null left
Edge
Add to Cart
 
Description

Description

Description: The TRFK4 antibody reacts with mouse interleukin-5 (IL-5), also known as BCDF-alpha and eosinophil differentiation factor (EDF). This 15-20 kDa cytokine is secreted by Th2 cells and exists a homodimer. Applications Reported: TRFK4 has been reported for use in detection of mouse IL-5 by ELISA. Applications Tested: The TRFK4 antibody has been tested as the detection antibody in a sandwich ELISA for analysis of mouse Interleukin-5 (IL-5) in combination with the purified TRFK5 (14-7052) antibody for capture and recombinant mouse IL-5 (14-8051) as the standard. A suitable range of concentrations of this antibody for ELISA detection is 0.5-2 μg/mL. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 1000 pg/mL - 8 pg/mL should be included in each ELISA plate. Filtration: 0.2 μm post-manufacturing filtered.

IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
Specifications

Specifications

IL-5
0.5 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
B-cell differentiation factor I; B-cell growth factor II; BCGF-II; colony-stimulating factor, eosinophil; cytotoxic T-lymphocyte inducer; EDF; Eosinophil differentiation factor; IL5; IL-5; ILN; Interleukin; Interleukin 5; Interleukin 5 (colony-stimulating factor eosinophil); Interleukin 5 (colony-stimulating factor, eosinophil); Interleukin5; interleukin-5; T-cell replacing factor; TRF
Il5
Primary
4°C, store in dark, DO NOT FREEZE!
Il5
TRFK4
Immunostaining
Biotin
Rat
Mouse
P04401
16191
IgG2a κ
Affinity chromatography
Antibody
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Documents

Documents

Product Certifications

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