Invitrogen™ IL-6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PP690

Catalog No. PIPP690

Description

PP690 targets IL-6 in WB applications and shows reactivity with Porcine samples. The PP690 immunogen is recombinant porcine IL-6. PP690 detects IL-6 which has a predicted molecular weight of approximately 21 kDa. This product is a Low Endotoxin formulation. This product has been tested for endotoxins by limulus amoebocyte lysate (LAL) assay and contains an endotoxin concentration of less than or equal to 10 endotoxin units per milligram (EU/mg).

IL-6 is a gene that encodes a cytokine that plays a role in inflammation and the maturation of B cells. The protein produced by this gene is an endogenous pyrogen that can induce fever in people with autoimmune diseases or infections. The gene is primarily expressed at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). Diseases associated with IL6 include Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile.

Specifications

• Antigen: IL-6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Il6
• Gene Alias: B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 399500
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1.0 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P26893
• Gene Symbols: Il6
• Immunogen: Recombinant porcine IL-6.
• Quantity: 1 mg
• Primary or Secondary: Primary
• Target Species: Pig
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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