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Invitrogen™ IL-6 Receptor Monoclonal Antibody (B-N12)

Catalog No. AHR0961
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AHR0961 100 μg
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Catalog No. AHR0961 Supplier Invitrogen™ Supplier No. AHR0961
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Description

Mouse Monoclonal Antibody

IL-6 Receptor Monoclonal Antibody for Flow, ELISA

Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL-6 Receptor
Applications ELISA, Flow Cytometry
Classification Monoclonal
Clone B-N12
Concentration 2.3 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.2
Gene IL6R
Gene Accession No. P08887
Gene Alias CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; IL6R; IL-6R; IL-6R 1; IL-6R subunit alpha; IL6R1; IL-6R-1; Il6ra; IL-6RA; IL-6R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991
Gene Symbols IL6R
Host Species Mouse
Immunogen CHO cells transfected with cDNA produced from the gp80 IL-6 receptor mRNA.
Purification Method Purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3570
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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