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Invitrogen™ IL-6 Receptor Recombinant Rabbit Monoclonal Antibody (9S8Q5)

Catalog No. MA557953
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MA557953 20 μL
MA557954 100 μL
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Catalog No. MA557953 Supplier Invitrogen™ Supplier No. MA557953
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Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: LVLGSCRALE VANGTVTSLP GATVTLICPG KEAAGNVTIH WVYSGSQNRE WTTTGNTLVL RDVQLSDTGD YLCSLNDHLV GTVPLLVDVP PEEPKLSCFR KNPLVNAICE WRPSSTPSPT TKAVLFAKKI NTTNGKSDFQ VPCQYSQQLK SFSCQVEILE GDKVYHIVSL CVANSVGSKS SHNEAFHSLK MVQPDPPANL VVSAIPGRPR WLKVSWQHPE TWDPSYYLLQ FQLRYRPVWS KEFTVLLLPV AQYQCVIHDA LRGVKHVVQV RGKEELDLGQ WSEWSPEVTG TPWIAEPRTT PAGILWNPTQ VSVEDSANHE DQYESSTEAT SVLAPVQE.

Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL-6 Receptor
Applications ELISA, Flow Cytometry, Western Blot
Classification Recombinant Monoclonal
Clone 9S8Q5
Concentration 1.07 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3
Gene Il6ra
Gene Accession No. P22272
Gene Alias CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; IL6R; IL-6R; IL-6R 1; IL-6R subunit alpha; IL6R1; IL-6R-1; Il6ra; IL-6RA; IL-6R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991
Gene Symbols Il6ra
Host Species Rabbit
Immunogen Recombinant Protein (or fragment)
Purification Method Protein A
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16194
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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