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Invitrogen™ IL17RA Recombinant Rabbit Monoclonal Antibody (6Q2U9)
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Catalog No. PIMA535663
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PIMA535663 100 μL
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Catalog No. PIMA535663 Supplier Invitrogen™ Supplier No. MA535663
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: GCSRPAMVLT DPHTPYEEEQ RQSVQSDQGY ISRSSPQPPE GLTEMEEEEE EEQDPGKPAL PLSPEDLESL RSLQRQLLFR QLQKNSGWDT MGSESEGPSA.

Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F. IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL17RA
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 6Q2U9
Concentration 0.32 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.05% BSA and 0.02% sodium azide; pH 7.3
Gene Il17ra
Gene Accession No. Q60943
Gene Alias AW538159; CANDF5; CD127; CD217; CDw217; hIL-17R; IL-17 receptor A; IL17R; Il17ra; IL-17RA; interleukin 17 receptor A; interleukin-17 receptor A; MGC10262; VDw217
Gene Symbols Il17ra
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16172, 312679
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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