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Invitrogen™ IL17RA Polyclonal Antibody
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Catalog No. PIPA5101326
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100 μL
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PIPA5101326 100 μL
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Catalog No. PIPA5101326 Supplier Invitrogen™ Supplier No. PA5101326
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total IL17RA.

Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F. IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL17RA
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Il17ra
Gene Accession No. Q60943, Q96F46
Gene Alias AW538159; CANDF5; CD127; CD217; CDw217; hIL-17R; IL-17 receptor A; IL17R; Il17ra; IL-17RA; interleukin 17 receptor A; interleukin-17 receptor A; MGC10262; VDw217
Gene Symbols Il17ra
Host Species Rabbit
Immunogen A synthesized peptide derived from human IL17RA(Accession Q96F46), corresponding to amino acid residues F146-C196.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16172, 23765, 312679
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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