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Invitrogen™ IL23R Recombinant Rabbit Monoclonal Antibody (K03_1K44)

Catalog No. MA564578
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MA564578 50 μL
MA563119 100 μL
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Catalog No. MA564578 Supplier Invitrogen™ Supplier No. MA564578
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Rabbit Recombinant Monoclonal Antibody

IL23R Recombinant Monoclonal Antibody for Western Blot

IL-23R is a 629 aa, novel subunit of the receptor for cytokine IL23A/IL23 which pairs with the receptor molecule IL12RB1/IL12R beta 1and thus take part in IL23A signaling. Signal transduction analysis confirms that this protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. Alternative splicing results in six spliced isoforms of IL-23R. Reports suggest that IL-23R plays an important role in psoriasis pathogenesis and is also a potential therapeutic target in inflammatory bowel disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL23R
Applications Western Blot
Classification Recombinant Monoclonal
Clone K03_1K44
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.5% BSA, 50% glycerol and 0.09% sodium azide
Gene Il23r
Gene Accession No. Q5VWK5, Q8K4B4
Gene Alias IBD17; IL 23R; IL-23 receptor; IL23R; IL-23R; interleukin 23 receptor; interleukin 23 receptor-like; interleukin-23 receptor
Gene Symbols Il23r
Host Species Rabbit
Immunogen Recombinant human IL23R protein.
Purification Method Protein A/G
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 149233, 209590
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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