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Invitrogen™ IL24 Monoclonal Antibody (OTI4E1)
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Catalog No. PIMA527141
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100 μL
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PIMA527141 100 μL
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Catalog No. PIMA527141 Supplier Invitrogen™ Supplier No. MA527141
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Description

Mouse Monoclonal Antibody

IL24 Monoclonal Antibody for Western Blot, IHC (P)

Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL24
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI4E1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene IL24
Gene Accession No. Q13007
Gene Alias C49A; Cytokine-like protein Mob-5; FISP; IL 24; IL10B; Il24; IL-24; IL-4-induced secreted protein; Interleukin; interleukin 24; interleukin-24; Mda7; MDA-7; melanocyte-associated Mda-7; melanoma differentiation-associated gene 7 protein; Mob5; ST16; suppression of tumorigenicity 16 (melanoma differentiation); Suppression of tumorigenicity 16 protein; Th2-specific cytokine FISP
Gene Symbols IL24
Host Species Mouse
Immunogen Human recombinant protein fragment corresponding to amino acids 52-206 of IL24 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11009
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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