Invitrogen™ IL24 Monoclonal Antibody (OTI4E1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527141

Catalog No. PIMA527141

Description

IL24 Monoclonal Antibody for Western Blot, IHC (P)

Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.

Specifications

• Antigen: IL24
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q13007
• Gene Symbols: IL24
• Immunogen: Human recombinant protein fragment corresponding to amino acids 52-206 of IL24 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI4E1
• Conjugate: Unconjugated
• Gene: IL24
• Gene Alias: C49A; Cytokine-like protein Mob-5; FISP; IL 24; IL10B; Il24; IL-24; IL-4-induced secreted protein; Interleukin; interleukin 24; interleukin-24; Mda7; MDA-7; melanocyte-associated Mda-7; melanoma differentiation-associated gene 7 protein; Mob5; ST16; suppression of tumorigenicity 16 (melanoma differentiation); Suppression of tumorigenicity 16 protein; Th2-specific cytokine FISP
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11009
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid