IL2RB Mouse anti-Human, Clone: OTI1D12, liquid, TrueMAB™

Catalog No.	Quantity
50-168-4487	100 μL

Catalog No. 50-168-4487 Supplier OriGene Supplier No. TA812258

Description

Mouse Monoclonal Antibody

CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and is present in 3 forms. The low affinity form of CD122 is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from CD122. The protein encoded by the CD122 gene represents the beta subunit and is a type I membrane protein. Diseases associate with CD122 protein dysfunction include oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.

Specifications

• Antigen: IL2RB
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI1D12
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: IL2RB
• Gene Accession No.: P14784
• Gene Alias: CD122, IL15RB, P70-75
• Gene Symbols: IL2RB
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 27-240+Mouse FC of human IL2RB produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3560
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1