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IL32 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501726857 Shop All Proteintech Group Inc Products
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50-172-6857 150 μL
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Catalog No. 50-172-6857 Supplier Proteintech Group Inc Supplier No. 110791AP150UL
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Rabbit Polyclonal Antibody

Interleukin-32 (IL-32) was initially identified as a transcript (NK4) that is selectively expressed in lymphocytes and NK cells and whose expression is increased following activation by IL-2. It was later re-isolated from an IL-18-treated lung carcinoma cell line and re-named IL-32. IL-32 is unusual in that it does not share sequence homology with known cytokine families and is highly expressed in immune tissues, existing in at least four differentially spliced isoforms. Because treatment of human monocytic and mouse macrophage cells with IL-32 induces several proinflammatory cytokines such as TNF-a, IL-8 and MIP-2, and because it is also induced in human peripheral lymphocyte cells after mitogen stimulation and in epithelial cells by IFN-gamma, it has been suggested that IL-32 may play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis.

Specifications

Antigen IL32
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene IL32
Gene Accession No. P24001
Gene Alias IL 32, IL 32alpha, IL 32beta, IL 32delta, IL 32gamma, IL32, interleukin 32, Natural killer cells protein 4, NK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd
Gene Symbols IL32
Host Species Rabbit
Immunogen IL32 Fusion Protein Ag1484
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9235
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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