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Enzo Life Sciences IM-54 (1mg). CAS: 861891-50-1

Supplier: Enzo Life Sciences ALX430137M001

Cell permeable inhibitor of necrosis. Selectively blocks oxidative stress-induced necrotic cell death (~3µM IM-54 prevented ~50% cell death in HL60 cells exposed to 100µM H2O2). Does not protect against etoposide-induced apoptosis or display antioxidant properties. Does not affect S6K1 and PKC kinase activities at concentrations of 50µM. Alternative name: 2-(1H-indol-3-yl)-3-pentylamino-maleimide. Purity: ≥98% (HPLC). Appearance: Yellow powder. Solubility: Soluble in DMSO (100mg/ml), dichloromethane, 100% ethanol or methanol (10mg/ml). Long Term Storage: -20°C.
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