Novus Biologicals™ Imiquimod, TLR7 ligand

Description

Applications: Functional, In vitro assay, Ligand Activation

Imiquimod, TLR7 ligand is an imidazoquinoline amine analog to guanosine. As a synthetic molecule of the Imidazoquinoline family, it has potent immunostimulatory activity. Imiquimod has been shown to activate only TLR7. This activation is MyD88 dependant and leads to the induction of the transcription factor NF-kB. Buffer: 125μg in 50μL of DMSO (formerly supplied in sterile water) Endotoxin Note: <0.001 EU/μg MW: 276.8

Specifications

• Concentration: 2.5 mg/mL
• Formulation: C₁₄H₁₆N₄, HCl
• Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Quantity: 0.125 mg
• For Use With (Application): This product is useful for activation of TLR7 and stimulation of TLR7 has been achieved with 5 to 10μL. Use in ligand activation, functional, and in vitro reported in scientific literature (PMID 25957979)
• Target: Imiquimod, TLR7 ligand
• Species: Human/Mouse

For Research Use Only