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IMP3 Polyclonal Antibody, Bethyl Laboratories

Catalog No. p-7142165
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50-156-5100 20 μL
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Catalog No. 50-156-5100 Supplier Bethyl Laboratories, Inc Supplier No. A303425AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family and is expressed during embryogenesis and in some maligcies. IMP-3 is expressed in maligt melanoma but not in benign nevi, even when dysplastic features are present; IMP-3 is expressed in a significantly higher proportion of melanomas than Spitz nevi; and IMP-3 is expressed in metastatic melanomas significantly more than in thin melanomas. IMP-3 appears to be involved in the progression of maligt melanoma and may play an important role in the regulation of the biologic behavior of this tumor.

Specifications

Antigen IMP3
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene IGF2BP3
Gene Accession No. O00425
Gene Alias CT98, IMP-3, IMP3, KOC1, VICKZ3, IGF II mRNA binding protein 3, IGF-II mRNA-binding protein 3, IGF2 mRNA-binding protein 3, KH domain containing protein overexpressed in cancer, KH domain-containing protein overexpressed in cancer, VICKZ family member 3, cancer/testis antigen 98, hKOC, insulin-l
Gene Symbols IGF2BP3
Host Species Rabbit
Immunogen Between 1 and 50
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10643
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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