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Invitrogen™ IMPA1 Monoclonal Antibody (2177CT172.34.52)
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Catalog No. PIMA537791
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200 μL
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Catalog No. Quantity
PIMA537791 200 μL
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Catalog No. PIMA537791 Supplier Invitrogen™ Supplier No. MA537791
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Description

Mouse Monoclonal Antibody

IMPA1 Monoclonal Antibody for Western Blot

IMPA1, also known as Myo-inositol monophosphatase 1, is responsible for the procurement of inositol that is required for synthesis of phosphatidylinositol and polyphosphoinositides. IMPA1 exists as a homodimer and has been identified as the pharmacological target for lithium action in the brain. IMPA1 is the principal enzyme of the phosphatidyl inositol signaling pathway, and inhibition of inositol monophosphatase hydrolysis may underlie the anti-manic and anti-depressant actions of Li+. Studies indicate that a variation in the 277 codon coding region of the IMPA1 gene has not been observed in manic-depressive patients, therefore suggesting that polymorphisms or mutations in the noncoding regions of this gene may influence the lithium response in psychiatric patients.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IMPA1
Applications Western Blot
Classification Monoclonal
Clone 2177CT172.34.52
Concentration 0.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Impa1
Gene Accession No. P29218
Gene Alias 2610002K09Rik; 2900059K10Rik; AI325909; D-galactose 1-phosphate phosphatase; IMP; IMP 1; IMPA; IMPA1; Impa1-L; IMPase 1; inositol (myo)-1(or 4)-monophosphatase 1; inositol monophosphatase 1; inositol(myo)-1(or 4)-monophosphatase 1; inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; myo-inositol monophosphatase 1; testicular tissue protein Li 94
Gene Symbols Impa1
Host Species Mouse
Immunogen recombinant protein from the human region of human IMPA1.
Purification Method Protein G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3612
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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Safety and Handling

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