Invitrogen™ Importin 8 Polyclonal Antibody

Catalog No.	Quantity
01-675-216	100 μg

Catalog No. 01-675-216 Supplier Invitrogen™ Supplier No. PA141599

Description

Rabbit Polyclonal Antibody

Importin 8 Polyclonal Antibody for Western Blot, ICC/IF

Importin 8 is a 1037 amino acidnuclear protein with a RAN binding site. It belongs to RAN-binding protein super family and hence shares an N-terminal sequence motif with importin-beta that appears to account for RAN GTP binding. It binds to the nuclear pore complex (NPC) and is well known as a transport carrier that mediates nuclear import of ribosomal proteins with a classical nuclear localization signal. Importin 8 works by binding to the nuclear pore complex and, along with RANGTP and RANBP1, inhibits the GAP stimulation of the RAN GTPase. Along with transportin it also helps in the nuclear import of SRP19.

Specifications

• Antigen: Importin 8
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1.0 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% sodium azide
• Gene: IPO8
• Gene Accession No.: O15397
• Gene Alias: 6230418K12Rik; Abcc10; ATP-binding cassette, sub-family C (CFTR/MRP), member 10; C130009K11Rik; FLJ26580; imp8; importin 8; importin-8; IPO8; MRP7; Om1; OM-1; oocyte maturation 1; RAN binding protein 8; ran-binding protein 8; RANBP8
• Gene Symbols: IPO8
• Host Species: Rabbit
• Immunogen: A portion of amino acids 850-900 of human Importin-8.
• Purification Method: Protein G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10526
• Target Species: Human, Monkey
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG