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INCENP Rabbit anti-Human, Mouse, Rat, Polyclonal, liquid, OriGene
SDP

Catalog No. 501684814
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50-168-4814 100 μL
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Catalog No. 50-168-4814 Supplier OriGene Supplier No. TA890129
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Rabbit Polyclonal Antibody

In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and ′passenger,′ or transiently interacting, proteins. The constitutive proteins include CENPA (centromere protein A), CENPB, CENPC1, and CENPD. The term ′passenger proteins′ encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle. These include CENPE; MCAK; KID; cytoplasmic dynein; CliPs; and CENPF/mitosin. The inner centromere proteins (INCENPs), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis.

Specifications

Antigen INCENP
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene INCENP
Gene Accession No. Q9NQS7, Q9WU62
Gene Alias inner centromere protein
Gene Symbols Incenp
Host Species Rabbit
Immunogen Recombit protein of human INCENP
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16319, 293733, 3619
Target Species Human, Mouse, Rat
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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