Invitrogen™ Influenza A NP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532242

Catalog No. PIPA532242

Description

Recommended positive controls: H1N1-infected H1299, DF1 (Influenza A virus treatment for 10hr), influenza virus (A/WSN/33) infected MDCK. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The nucleoprotein (NP) of Influenza A virus encapsidates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. 'NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56' (Portela et al 2002).

Specifications

• Antigen: Influenza A NP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: Influenza nucleoprotein
• Immunogen: Recombinant protein of Influenza A virus Nucleoprotein (A/WSN/1933(H1N1)). The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 0.23 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG