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Invitrogen™ INHBB Monoclonal Antibody (C11), Invitrogen™

Catalog No. p-7240977
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100 μL
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Catalog No. Quantity
PIMA543692 20 μL
PIMA543691 100 μL
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Catalog No. PIMA543692 Supplier Invitrogen™ Supplier No. MA543692
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Description

Mouse Monoclonal Antibody

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.
TRUSTED_SUSTAINABILITY

Specifications

Antigen INHBB
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone C11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene INHBB
Gene Accession No. P09529
Gene Alias activin AB beta polypeptide; activin betaB; activin beta-B chain; INHBB; Inhibin beta B chain; inhibin beta B subunit; inhibin beta subunit B; inhibin beta-B; inhibin, beta B; Inhibin, beta-2
Gene Symbols INHBB
Host Species Mouse
Immunogen Recombinant INHbB (Gly293-Ala407) expressed in E. coli.
Purification Method Protein A/G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3625
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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