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Inhibin beta A Mouse anti-Human, Porcine, Clone: 1F8D8, Proteintech
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Catalog No. 501736439 Shop All Proteintech Group Inc Products
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Catalog No. 50-173-6439 Supplier Proteintech Group Inc Supplier No. 603521IG150UL
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Mouse Monoclonal Antibody

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Activin A mutations are associated with fibrodysplasia ossificans progressive.

Specifications

Antigen Inhibin beta A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1F8D8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene INHBA
Gene Accession No. P03970, P08476
Gene Alias Activin beta A chain, EDF, FRP, INHBA, INHBA-Specific, Inhibin beta A chain, inhibin, beta A
Gene Symbols INHBA
Host Species Mouse
Immunogen Peptide
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3624, 397093
Target Species Human, Pig
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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