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INPP5D Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. p-7208501 Shop All Proteintech Group Inc Products
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50-173-2491 150 μL
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Catalog No. 50-173-2491 Supplier Proteintech Group Inc Supplier No. 196941AP150UL
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Description

Rabbit Polyclonal Antibody

This antibody is specific to INPP5D.

an SH2-containing inositol phosphatase. A hemopoietic-specific phosphatase that regulates cell survival, growth, cell cycle arrest and apoptosis. Hydrolyzes Ins(1, 3, 4, 5)P4 and PtdIns(3, 4, 5)P3. A cytosolic protein with a SH2 domain in its N-terminus and two NPXY Shc binding motifs at its C-terminus. Upon receptor cross-linking, SHIP is first recruited to the plasma membrane by its SH2, followed by tyrosine phosphorylation on the NPXY motif. Both membrane relocalization and phosphorylation are essential for its regulatory function. Associates with SHC after cytokine stimulation.

Specifications

Antigen INPP5D
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.26 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene INPP5D
Gene Accession No. P97573, Q92835, Q9ES52
Gene Alias hp51CN, INPP5D, p150Ship, SHIP, SHIP 1, SHIP1, SIP 145
Gene Symbols INPP5D
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16331, 3635, 54259
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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