Invitrogen™ INPP5J Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA576968

Catalog No. PIPA576968

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Inositol and phosphatidylinositol phosphates are important for numerous cellular processes, including neuronal survival and signal transductions from growth factors, neurotransmitters and G protein coupled receptors. INPP5J (inositol polyphosphate-5-phosphatase J), also known as phosphatidylinositol 4,5-bisphosphate 5-phosphatase A, PIPP (proline-rich inositol polyphosphate 5-phosphatase), PIB5PA or INPP5, is a 1,006 amino acid cytoplasmic protein that assists in the conversion of inositol 1,4-bisphosphate from inositol 1,4,5-trisphosphate. Expressed in lung, stomach, kidney, brain, small intestine and heart, INPP5J localizes to membrane ruffles, where it may also participate in modulating inositol and phosphatidylinositol polyphosphate-binding proteins. Encoded by a gene located on human chromosome 22, INPP5J undergoes alternative splicing to produce three isoforms.

Specifications

• Antigen: INPP5J
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: INPP5J
• Gene Alias: Inositol polyphosphate 5-phosphatase J; inositol polyphosphate-5-phosphatase J; Inpp; INPP5; Inpp5j; phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A; phosphatidylinositol 4,5-bisphosphate 5-phosphatase A; Pib5pa; Pipp; Proline-rich inositol polyphosphate 5-phosphatase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170835, 171088, 27124
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P59644, Q15735, Q9JMC1
• Gene Symbols: INPP5J
• Immunogen: Recombinant full length Human INPP5J.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG