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Invitrogen™ Insulin Polyclonal Antibody

Catalog No. PA129383
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7 mL
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Catalog No. Quantity
PA129383 7 mL
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Catalog No. PA129383 Supplier Invitrogen™ Supplier No. PA129383

Description

Guinea Pig Polyclonal Antibody

A recommended positive control is human pancreas.

Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Insulin is 51-amino acid polypeptide product produced from a precursor peptide, proinsulin. Proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds and one molecule of C-peptide. Insulin deficiency results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Insulin
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 10 μg/mL
Conjugate Unconjugated
Formulation Proprietary buffer with no preservative
Gene INS
Gene Accession No. P01308
Gene Alias AA986540; IDDM; IDDM1; IDDM2; ILPR; INS; Ins1; Ins-1; Ins2; Ins-2; Ins2-rs1; InsII; Insulin; insulin 1; insulin 2; Insulin A chain; Insulin B chain; insulin I; insulin II; insulin-1; Insulin-1 A chain; Insulin-1 B chain; Insulin-2; Insulin-2 A chain; Insulin-2 B chain; IRDN; Mody; MODY10; Mody4; preproinsulin; proinsulin
Gene Symbols INS
Host Species Guinea Pig
Immunogen Purified human insulin conjugated to carrier protein.
Purification Method purified
Quantity 7 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3630
Target Species Human
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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