Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA584245

Invitrogen™ Involucrin Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA584245
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA584245 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA584245 Supplier Invitrogen™ Supplier No. PA584245
Only null left
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: QQHTLPVTLS PALSQELLKT VPPPVNTHQE QMKQPTPLPP PCQKVPVELP VEVPSKQEEK HMTAVKGLPE QECEQ Highest antigen sequence indentity to the following orthologs: Rat - 53%, Mouse - 52%.

Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. Involucrin is expressed in a range of stratified squamous epithelia, including the cornea. In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures it is expressed by all cells that have left the basal layer. Involucrin expression is abnormal in squamous cell carcinomas and premalignant lesions and is reduced in severe dysplasias of the larynx and cervix. Its gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Involucrin
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene IVL
Gene Accession No. P07476
Gene Alias 1110019C06Rik; involucrin; IVL
Gene Symbols IVL
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human IVL. Recombinant protein control fragment (Product #RP-101412).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3713
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.