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Invitrogen™ INVS Polyclonal Antibody
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Catalog No. PIPA587787
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100 μL
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PIPA587787 100 μL
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Catalog No. PIPA587787 Supplier Invitrogen™ Supplier No. PA587787
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MNKSENLLFA GSSLASQVHA AAVNGDKGAL QRLIVGNSAL KDKEDQFGRT PLMYCVLADR LDCADALLKA GADVNKTDHS QRTALHLAAQ; Positive Samples: 293T, K-562, Mouse liver, Mouse kidney; Cellular Location: Cell projection, Cytoplasm, Membrane, Nucleus, Peripheral membrane protein, cilium, cytoskeleton, spindle.

This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen INVS
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.58 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Invs
Gene Accession No. O89019, Q9Y283
Gene Alias INV; inversin; Inversion of embryo turning homolog; inversion of embryo turning protein; inversion of embryonic turning; INVS; nephrocystin 2; nephrocystin-2; NPH2; NPHP2; RGD1563359
Gene Symbols Invs
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human INVS (NP_0552402).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16348, 27130
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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