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Invitrogen™ IPO5 Polyclonal Antibody
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Catalog No. PIPA5102541
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PIPA5102541 100 μL
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Catalog No. PIPA5102541 Supplier Invitrogen™ Supplier No. PA5102541
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total IPO5.

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IPO5
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene IPO5
Gene Accession No. O00410, Q8BKC5
Gene Alias 1110011C18Rik; 5730478E03Rik; AA409333; C76941; IMB3; imp5; importin 5; importin beta-3 subunit; importin subunit beta-3; Importin-5; IPO 5; IPO5; karyopherin (importin) beta 3; Karyopherin beta 3; karyopherin beta-3; Kpnb3; MGC2068; Pse1; RAN binding protein 5; Ran_GTP binding protein 5; ran-binding protein 5; RanBP 5; Ranbp5
Gene Symbols IPO5
Host Species Rabbit
Immunogen A synthesized peptide derived from human IPO5(Accession O00410), corresponding to amino acid residues G795-I845.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 306182, 3843, 70572
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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