Invitrogen™ IRAK-M Polyclonal Antibody

Catalog No.	Quantity
PIPA517473	100 μL

Catalog No. PIPA517473 Supplier Invitrogen™ Supplier No. PA517473

Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody.

IRAK3 serine/threonine kinase or interleukin-1 receptor-associated kinase 3 is a member of the interleukin-1 receptor-associated kinase protein family which are essential components of the Toll/IL-R immune signal transduction pathways. IRAK3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. IRAK3 mediates critical aspects of innate immunity that result in an immunocompromised state during sepsis. Mutations in IRAK3 are associated with a susceptibility to asthma.

Specifications

• Antigen: IRAK-M
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 29 μg/mL
• Conjugate: Unconjugated
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene: IRAK3
• Gene Accession No.: Q9Y616
• Gene Alias: 4833428C18Rik; AI563835; ASRT5; FLJ13601; IL-1 receptor-associated kinase M; interleukin 1 receptor associated kinase 3; interleukin-1 receptor-associated kinase 3; IRAK3; IRAK-3; IRAKM; IRAK-M
• Gene Symbols: IRAK3
• Host Species: Rabbit
• Immunogen: Synthetic peptide corresponding to residues near the carboxy-terminus of human IRAK-M.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11213
• Target Species: Human, Monkey
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG