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Invitrogen™ IRAK4 Polyclonal Antibody
Goat Polyclonal Antibody
Supplier: Invitrogen™ PA19057
Description
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
IL-1 receptor associated kinases (IRAKs) are serine/threonine kinases involved in signaling via Toll/IL-1 pathways. Overexpression of IRAK-4 activates NF-kappa-B and MAPK pathways. IRAK-4 interacts with and phosphorylates IRAK-1. IRAK-4-deficient animals are completely resistant to the challenge with LPS. Animals and humans lacking IRAK-4 are impaired in their responses to viral and bacterial challenges. Members in IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory responses and in innate immunity.
Specifications
IRAK4 | |
Polyclonal | |
Unconjugated | |
IRAK4 | |
8430405M07Rik; 9330209D03Rik; interleukin 1 receptor associated kinase 4; interleukin-1; interleukin-1 receptor-associated kinase 4; IPD1; Irak4; IRAK-4; NY-REN-64; REN64; renal carcinoma antigen NY-REN-64 | |
Goat | |
Ammonium sulfate precipitation | |
RUO | |
51135 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
0.5 mg/mL | |
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
Q9NWZ3 | |
IRAK4 | |
Synthetic peptide corresponding to the N terminus amino acids NKPITPSTYVRC (aa 2-14). | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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