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Invitrogen™ IREB2 Monoclonal Antibody (9D1)
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Catalog No. PIMA542529
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100 μL
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PIMA542529 100 μL
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Catalog No. PIMA542529 Supplier Invitrogen™ Supplier No. MA542529
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Description

Mouse Monoclonal Antibody

Positive Control: Jurkat cell lysate, Daudi cell lysate, human liver tissue lysate, human placenta tissue. Subcellular Location: Cytoplasm.

Iron regulatory protein 2 (IRP2) is a central post-transcriptional regulator of cellular and systemic iron metabolism. It is a cytosolic RNA-binding protein that binds to stem-loop structures. IRP2 is regulated by iron-mediated proteolysis. Hypoxia is important for normal tissue physiology as well as being a component of several pathophysiological conditions, including heart and cerebrovascular diseases and tumor growth. Because iron and oxygen are closely related, IRP2 also plays a role during hypoxia (low oxygen).
TRUSTED_SUSTAINABILITY

Specifications

Antigen IREB2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 9D1
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene IREB2
Gene Accession No. P48200
Gene Alias ACO3; D9Ertd85e; FLJ23381; im:7153062; Ireb2; IRE-BP 2; IREBP2; Iron regulatory protein 2; iron responsive element binding protein 2; iron-regulatory protein 2; iron-responsive element binding protein 2; iron-responsive element-binding protein 2; Iron-responsive element-binding protein 2-like protein; IRP2; IRP2AD
Gene Symbols IREB2
Host Species Mouse
Immunogen Recombinant protein within human IREB2 aa 1-963.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3658
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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