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Invitrogen™ IREB2 Polyclonal Antibody
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Catalog No. APPA6544
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100 μL
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APPA6544 100 μL
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Catalog No. APPA6544 Supplier Invitrogen™ Supplier No. PA116544
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Description

Rabbit Polyclonal Antibody

This antibody has 94% sequence homology with human, primate and rat. Suggested positive control: 3T3 whole cell lysate. Preliminary results have shown poor reactivity against human protein. Immunogen sequence homology: primate and rat (94%) proteins.

Iron regulatory protein 2 (IRP2) is a central post-transcriptional regulator of cellular and systemic iron metabolism. It is a cytosolic RNA-binding protein that binds to stem-loop structures. IRP2 is regulated by iron-mediated proteolysis. Hypoxia is important for normal tissue physiology as well as being a component of several pathophysiological conditions, including heart and cerebrovascular diseases and tumor growth. Because iron and oxygen are closely related, IRP2 also plays a role during hypoxia (low oxygen).
TRUSTED_SUSTAINABILITY

Specifications

Antigen IREB2
Applications Gel Shift, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.15 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% sodium azide
Gene IREB2
Gene Accession No. P48200, Q811J3
Gene Alias ACO3; D9Ertd85e; FLJ23381; im:7153062; Ireb2; IRE-BP 2; IREBP2; Iron regulatory protein 2; iron responsive element binding protein 2; iron-regulatory protein 2; iron-responsive element binding protein 2; iron-responsive element-binding protein 2; Iron-responsive element-binding protein 2-like protein; IRP2; IRP2AD
Gene Symbols IREB2
Host Species Rabbit
Immunogen A synthetic peptide made to an internal portion of the murine IRP2 protein sequence (between residues 100-200).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3658, 64602
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov
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