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IRF4 Mouse anti-Human, Porcine, Rat, Clone: 1A12D5, Proteintech
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Catalog No. p-7213140 Shop All Proteintech Group Inc Products
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50-173-6877 150 μL
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Catalog No. 50-173-6877 Supplier Proteintech Group Inc Supplier No. 664511IG150UL
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Mouse Monoclonal Antibody

The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found.

Specifications

Antigen IRF4
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1A12D5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene IRF4
Gene Accession No. Q15306
Gene Alias interferon regulatory factor 4, IRF 4, IRF4, LSIRF, Multiple myeloma oncogene 1, MUM1, NF EM5
Gene Symbols Irf4
Host Species Mouse
Immunogen IRF4 Fusion Protein Ag25203
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100144625, 291100, 3662
Target Species Human, Pig, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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