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Invitrogen™ IRF4 Polyclonal Antibody
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Catalog No. PIPA521144
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100 μg
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Catalog No. Quantity
PIPA521144 100 μg
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Catalog No. PIPA521144 Supplier Invitrogen™ Supplier No. PA521144
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Description

Rabbit Polyclonal Antibody

A suggested positive control is Jurkat cell lysate. PA5-21144 can be used with blocking peptide PEP-1258.

The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IRF4
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene IRF4
Gene Accession No. Q15306, Q64287
Gene Alias AI385587; interferon regulatory factor 4; Irf4; IRF-4; LSIRF; Lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1; NF-EM5; PU.1 interaction partner; Sfpi1/PU.1 interaction partner; SHEP8; Spip; Transcriptional activator PIP
Gene Symbols IRF4
Host Species Rabbit
Immunogen A 16 amino acid peptide near the carboxy terminus of human IRF4.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16364, 291100, 3662
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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