Isonipecotamide, 98%

Description

CAS: 39546-32-2 | C6H12N2O | 128.18 g/mol

Isonipecotamide is used as a reactant for the preparation of Survival motor neuron (SMN) protein modulators, orally available naphthyridine protein kinase D inhibitors and heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase. It is also used to prepare phosphodiesterase 5 inhibitors. It is also used as a reactant for identification of small molecular inhibitors of importin-beta mediated nuclear import. It is also used as a fluorenylmethyloxycarbonyl - deprotection agent in organic synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Isonipecotamide is used as a reactant for the preparation of Survival motor neuron (SMN) protein modulators, orally available naphthyridine protein kinase D inhibitors and heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase. It is also used to prepare phosphodiesterase 5 inhibitors. It is also used as a reactant for identification of small molecular inhibitors of importin-beta mediated nuclear import. It is also used as a fluorenylmethyloxycarbonyl - deprotection agent in organic synthesis.

Solubility
Soluble in water.

Notes
Moisture sensitive. Hygroscopic. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 39546-32-2
• Molecular Formula: C6H12N2O
• Molecular Weight (g/mol): 128.18
• MDL Number: MFCD00038012
• InChI Key: DPBWFNDFMCCGGJ-UHFFFAOYSA-N
• Synonym: isonipecotamide, 4-piperidinecarboxamide, hexahydroisonicotinamide, 4-carbamoylpiperidine, isonipectoamide, piperidine-4-carboxylic acid amide, 4-piperdinecarboxamide, piperidin-4-carboxamid, iso nipecotamide, iso-nipecotamide
• PubChem CID: 3772
• IUPAC Name: piperidine-4-carboxamide
• SMILES: NC(=O)C1CCNCC1

• Melting Point: 148°C to 149°C
• Quantity: 10 g
• Beilstein: 112554
• Sensitivity: Hygroscopic
• Solubility Information: Soluble in water.
• Formula Weight: 128.18
• Percent Purity: 98%
• Chemical Name or Material: Isonipecotamide

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	254-501-6
TSCA	Yes
Recommended Storage	Ambient temperatures; Store under Nitrogen

SDS

RUO – Research Use Only