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Tocris Bioscience™ ITD 1
Selective inhibitor of TGF-β signaling; induces cardiomyocyte differentiation in ESCs
$335.24 - $1367.64
Specifications
| Purity | >98% |
|---|---|
| Content And Storage | -20°C |
| Product Type | ITD 1 |
| Molecular Weight (g/mol) | 415.52 |
| Inhibitors | ITD 1 |
Description
Selective inhibitor of TGF-β signaling (IC50 = 0.85 μM); displays little or no inhibition of activin, Wnt or BMP signaling pathways. Induces proteasomal degradation of the TGF-β type II receptor. Inhibits TGF-β-induced mesoderm formation from mouse embryonic stem cells (ESCs) during early differentiation; selectively promotes the differentiation of ESCs to cardiomyocytes in vitro between days 3-5. Does not induce differentiation of vascular smooth muscle cells or endothelial cells.Specifications
| >98% | |
| ITD 1 | |
| ITD 1 |
| -20°C | |
| 415.52 |
For Research Use Only
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