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Tocris Bioscience™ ITD 1

Selective inhibitor of TGF-β signaling; induces cardiomyocyte differentiation in ESCs

$233.00 - $952.00

Specifications

Product Type ITD 1
Inhibitors ITD 1
Molecular Weight 415.52
Purity >98
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-685-0R
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Tocris Bioscience™
5068/50
50mg
Each for $952.00
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50-681-0
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Tocris Bioscience™
5068/10
10mg
Each for $233.00
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Description

Description

Selective inhibitor of TGF-β signaling (IC50 = 0.85 μM); displays little or no inhibition of activin, Wnt or BMP signaling pathways. Induces proteasomal degradation of the TGF-β type II receptor. Inhibits TGF-β-induced mesoderm formation from mouse embryonic stem cells (ESCs) during early differentiation; selectively promotes the differentiation of ESCs to cardiomyocytes in vitro between days 3-5. Does not induce differentiation of vascular smooth muscle cells or endothelial cells.
Specifications

Specifications

ITD 1
ITD 1
415.52
>98
SDS
Product Certifications

For Research Use Only

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