Invitrogen™ ITFG2 Monoclonal Antibody (OTI 3D8)

Catalog No.	Quantity
PIMA525575	100 μL

Catalog No. PIMA525575 Supplier Invitrogen™ Supplier No. MA525575

Description

Mouse Monoclonal Antibody

ITFG2 Monoclonal Antibody for Western Blot, Flow

As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.

Specifications

• Antigen: ITFG2
• Applications: Flow Cytometry, Western Blot
• Classification: Monoclonal
• Clone: OTI 3D8
• Concentration: 0.34 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: ITFG2
• Gene Accession No.: Q969R8
• Gene Alias: 2700050P07Rik; AI646725; integrin alpha FG-GAP repeat containing 2; integrin-alpha FG-GAP repeat-containing protein 2; integrin-alpha FG-GAP repeat-containing protein 2; KICSTOR complex protein ITFG2; ITFG2; KICSTOR complex protein ITFG2; MDS028; RGD1311944
• Gene Symbols: ITFG2
• Host Species: Mouse
• Immunogen: Full length human recombinant protein of ITFG2 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 55846
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1